Wednesday, 28th November 6th Australian Health and Medical Research Congress 2012

• Not available at time of print - Peter Durie
• THE PANCREAS IN CYSTIC FIBROSIS ……AND HOW TO DIAGNOSE CYSTIC FIBROSIS. - Keith Chee Ooi
• Acute pancreatitis in children - Mark Oliver

• Osteoblast to Osteocyte Maturation is Accompanied by Changes in Epigenomic Modifications, Transcription Factor Binding Patterns, and Differential Response to 1,25-Dihydroxyvitamin D₃ and PTH - J Wesley Pike
• Genetic Control of Bone Remodelling - Emma Duncan
• ENU-induced mutant mice models to identify novel molecules that regulate bone homeostasis - Jiake Xu

• How Mutant Stem Cells Clonally Expand in your Skin: Sunlight, Stochasticity, and Non-mutational Events - Douglas Brash
• Activity and fate of epidermal stem cells in homeostasis and injury - Kiarash Khosrotehrani
• Defining the effect of endoplasmic reticulum (ER) stress-induction on melanoma growth by real-time cell cycle imaging - Nikolas K Haass
• The effect of genotype and sunscreen on the response of human skin cells in vivo to ultraviolet radiation - Elke Hacker
• Loss of Brm promotes the cell proliferative effects of ultraviolet radiation   - Nur mohammad monsur Hassan
• Ultraviolet irradiation of skin induces a long-lasting effect on dendritic cell precursors in bone marrow - Royce LX Ng

• Nanoparticle uptake and passage across the placenta: therapeutic applications. Symposium on Placental Transport - Jeff Keelan
• Sulfate supply to the fetus in human and animal gestation. - Paul A Dawson
• IMPAIRED LABYRINTH MORPHOGENESIS AND INTERHEMAL MEMBRANE FORMATION IN LY6E MUTANT MICE - David G Simmons
• Plasmodium falciparum Malaria Elicits Inflammatory Responses that Dysregulate Placental Amino Acid Transport - Philippe Boeuf

• Translational Research and the Coronary Slow Flow Phenomenon - John Beltrame
• Pathological versus physiological cardiac hypertrophy - Bianca C Bernardo
• Targeting Stress-Activated Protein Kinases in Cardiovascular Disease. - Dominic C Ng
• Mechanical Stretch Alters the Morphology and Function of Atrial Endocardial Endothelial Cells - Vesna Nikolova-Krstevski

• Shannon Entropy Localizes the Pivot of Rotors in Atrial Fibrillation - Anand Ganesan
• Effects of High Fat Diet on Atrial Electrophysiological Remodelling in Type II Diabetes: Electrophysiological Mapping Studies in a Pre-obese Mouse Model - Wei Wen Lim
• Riluzole reduces aconitine induced arrhythmias in an in-vivo­­ rat model - David G Morris
• Atrial Electrophysiological Remodelling in a Pre-Obese Mouse Model of Type II Diabetes: Intracellular Recording Studies - Melissa Neo
• Identifying modifier genes – using skeletal muscle actin disease as a model - Kristen Nowak
• In vitro culture and embryo transfer increases translation efficiency promoting heart growth in the sheep fetus - Monalisa Padhee
• Cardiovascular Risk Factors and Events are more frequent prior to the onset of Rheumatoid Arthritis than in the general population - Helen Pahau
• CaMKII and the heart: a differential activation profile in female and male myocardium - Antonia JA Raaijmakers
• A family history of type 2 diabetes mellitus is associated with lower heart rate variability in non-obese females. - Ms. Adriana Suker
• HRV Analysis of the heart beat may provide an additional means of diagnosing lung disease. - Laura Casey

• Annexin VIII is a prototypical substrate-induced gene involved in OC polarization and function and: is regulated by calcineurin-NFATc1 signalling - Tania N Crotti
• The role of mTORC1 in post natal skeletal development. - Mary Matthews
• Assessment of the Skeletal Phenotype of Aged Vitamin D Receptor (VDR) Knockout Mice: Is VDR Required for Healthy Bone? - Jackson W. Ryan
• Dietary calcium-mediated changes to circulating 1,25D levels arbitrate anabolic or anti-anabolic activities in Vitamin D Receptor over-expressed in mature osteoblasts mouse model (OSVDR mice). - Rahma Triliana
• The effects of 1,25-dihydroxyvitamin D on in vitro mineral deposition depend on the stage of osteoblast maturation and extracellular calcium concentration - Dongqing Yang
• Adequate 25-hydroxyvitamin D levels are required for collagen stabilisation and calcium deposition within the bone microenvironment - Ruth Zoehrer
• Protective effect of virgin coconut oil on bone loss in oestrogen deficient rats - Norliza Muhammad

• Ras, the Abstruse Elephant in the Room - Craig Logsdon

AGM from 14:15-15:00

• A Molecular Pre-operative Prognostic Nomogram for Resectable Pancreatic Cancer - David K Chang
• Influence of Apolipoprotein A-II in Pancreatic Cancer Cell Proliferation - Senthil Supramaniam
• Establishment of patient-derived subrenal capsule xenograft of pancreatic cancers in NOD/SCID mice:  potential models for drug responses of personalized chemotherapy - Aiqun Xue

• Epigenetic Control of Inflammation and Bone Loss using Histone Deacetylase Inhibitors. - Melissa D Cantley
• Sclerostin Stimulates Osteocyte Support of Osteoclast Activity by a RANKL-Dependent Pathway - Asiri R Wijenayaka
• Regional Heterogeneity of Trabecular Bone Microcrack Density in Association with Trabecular Microarchitecture and Bone Resorption in Whole Human Lumbar Vertebrae - Julia S Kuliwaba
• Vitamin D synthesis within osteoblasts and osteocytes mediates increased bone mineral apposition - Andrew G Turner
• Loss of lysosomal β-glucuronidase activity decreases osteoclast recruitment and activity. - Sharon Byers
• Hip bone marrow lesions in asymptomatic and osteoarthritic adults: prevalence, risk factors and significance - Luke P Dawson
• Inhibition of Wnt-β-catenin signalling pathway reduces bony but promotes cartilage repair at injured growth plate in rats - Cory J Xian
• Mechanical Loading Response In Trabecular Bone Is Abrogated By Sclerostin - A Direct Demonstration - Kamarul Ariffin Khalid

• Devil Facial Tumour Disease: evolution of a contagious cancer. - Katherine Belov
• Tasmanian Devil Facial Tumour Disease and recent progress - Gregory M Woods
• Identification and characterisation of a pro-tumourigenic cytokine in marsupial species. - Casey R Borthwick
• Resolvin E1 promotes resolution of inflammation in a model of an acute exacerbation of allergic asthma - Rakesh K. Kumar

• Placental Adaptations to Maternal Nutrition and Fetal Growth Demand: Implications for Programming. - Colin P Sibley

• Cytomegalovirus gene important for infection of placental trophoblasts and infection-dependent dysregulation of cytokine expression - William Rawlinson
• Maternal pre-eclampsia susceptibility gene mRNA levels are upregulated in decidua from severe pre-eclamptic pregnancies - Hannah EJ Yong
• Apolipoprotein A-I protects normal integration of the trophoblast into endothelial cellular networks in an in vitro model of Preeclampsia - Francesca Charlton
• Bioassay-directed discovery of pro-angiogenic molecules - Farzaneh Kordbacheh
• Isolation of trophoblast Hoescht side populations from human first trimester villi - Jo James

• Coenzyme Q10 Protects Against Diabetes-Induced Diastolic Dysfunction and Adverse Cardiac Remodelling in a Mouse Model of Type 1 Diabetes - Karina Huynh
• Characterization Of Substrate For Atrial Fibrillation In Obesity And Reversibility with Weight Reduction: An Ovine Study - Rajiv Mahajan
• Obesity Improves Myocardial Ischaemic Tolerance and 'RISK' Signalling in Middle-Aged Insulin-Insensitive Rats.  - Eugene Du Toit
• LOW INTRINSIC EXERCISE CAPACITY IN RATS PREDISPOSES TO AGE-DEPENDENT CARDIAC REMODELLING INDEPENDENT OF MACROVASCULAR FUNCTION - Rebecca H Ritchie
• Genetics of Heart Disease - Lauren P Hunt
• Sex, Genomics and the Cardiovascular System - Fadi J Charchar

Talk 1: NARF Postdoc Award

• Drugging the undruggable: Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53. - Ross D Hannan
• Identification and detection of both germline and somatic mutations contributing to predisposition and progression of haematological malignancies. - Hamish Scott
• Nedd4 family of ubiquitin ligases in physiology and disease - Sharad Kumar

• Cathepsin E as a novel marker of precursor lesions - Craig Logsdon
• Beta-Tubulins: Mediators of Chemoresistance in Pancreatic Cancer - Phoebe A Phillips
• Not available at time of print - Ross Smith

• Neural control of bone mass: Integration of bone, energy and glucose homeostasis - Paul Baldock
• Osteomacs are multifunctional contributors to bone repair and dynamics. - Allison Pettit
• Not available at time of print - Gerald Atkins
• Not available at time of print - Michelle McDonald

• Role of homeobox gene transcription factors in human placental vascular development. - Padma Murthi
• Regulation of the maternal vascular adaptations to pregnancy - Laura J Parry
• Recent advances in our understanding of hypertension in pregnancy. - Annemarie Hennessy

• Characterising myocardial injury with magnetic resonance imaging - Joseph Selvananyagam
• The Role of EGFR Transactivation in Mediating Cardioprotection. - Jason Peart
• CaMKII and the ischemic heart: for better or for worse? - James R Bell
• PDH Adaptation and Dysfunction in the Failing Human Heart - Freya Sheeran

• Regional Activation of the Cancer Genome by Long Range Epigenetic Remodelling  - Susan J Clark
• The genetics of metastatic melanoma- using our existing knowledge and high-throughput sequencing strategies to shed light on a rare form of melanoma - Ken Dutton-Regester
• A role of piRNA pathway genes in the mammalian ovary and in ovarian cancer - Frank Grützner
• Mapping naevus and melanoma genes utilising the ‘Collaborative Cross’ mice - Herlina Y Handoko
• Regulation of the SIRT1/p53/miR-34a axis in Human Keratinocytes - Katharine J Herbert